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Indomethacin increases the negative effect of cyclosporine on kidney function and reduces the effect of furosemideLasixand thiazide diuretics because of prostaglandin inhibition.
A blood thinner such as warfarinCoumadincyclosporineGengrafNeoralSandimmunedigoxindigitalisLanoxindiureticswater pillssuch as furosemideLasixlithiumEskalithLithobidmethotrexateRheumatrexTrexallprobenecidBenemidsteroidsprednisone and othersaspirin or other NSAIDsnon-steroidal anti-inflammatory drugssuch as diclofenacVoltarendiflunisalDolobidetodolacLodineflurbiprofenAnsaidibuprofenAdvilMotrinketoprofenOrudisketorolacToradolmefenamic acidPonstelmeloxicamMobicnabumetoneRelafennaproxenAleveNaprosynpiroxicamFeldeneand othersor a beta-blocker such as atenololTenorminbisoprololZebetalabetalolNormodyneTrandatemetoprololLopressorToprolnadololCorgardpropranololInderalInnoPransotalolBetapacetimololBlocadrenand others.
Indomethacin is used to treat pain or inflammation caused by many conditions such as arthritisgoutankylosing spondylitisbursitisor tendinitis.
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